Sachin Sarcoma Society
Gemcitabine

Gemcitabine

Gemcitabine is used for:

  • Pancreas and gallbladder cancer  
  • Non-small cell lung cancer
  • Urinary Bladder cancer
  • Soft-tissue sarcoma
  • Metastatic breast cancer
  • Ovarian cancer

Gemcitabine is given by infusion through a vein (intravenously, by IV)

Side Effects of Gemcitabine:

The following side effects are common (occurring in more than 30%) for patients taking gemcitabine:

  • Flu-like symptoms(muscle pain, fever, headache, chills, fatigue)
  • Fever  (within 6-12 hours of first dose)
  • Fatigue
  • Nausea (mild)
  • Vomiting
  • Poor appetite
  • Skin rash
  • Low blood counts (white and red blood cells and platelets may temporarily decrease).  This can put the patient at increased risk for infection, anemia, and/or bleeding.

The following are less common side effects (occurring in 10-29%) among patients receiving gemcitabine:

  • Diarrhea
  • Weakness
  • Hair loss
  • Mouth sores
  • Shortness of breath

In combination with Pazopanib, liver function tests should be specifically followed. They should be done every week.